Last edited by Tygok
Wednesday, July 22, 2020 | History

5 edition of Current Therapy of Von Willebrand"s Disease (Current Therapy of Von Willerbrand"s Disease, Vol 24, No 5) found in the catalog.

Current Therapy of Von Willebrand"s Disease (Current Therapy of Von Willerbrand"s Disease, Vol 24, No 5)

by M. M. P. Mannucci

  • 47 Want to read
  • 9 Currently reading

Published by S. Karger AG (Switzerland) .
Written in English

    Subjects:
  • Haematology,
  • Hematology,
  • Medical / Nursing,
  • Science/Mathematics

  • The Physical Object
    FormatPaperback
    Number of Pages64
    ID Numbers
    Open LibraryOL12930461M
    ISBN 103805560788
    ISBN 109783805560788

    Von Willebrand disease is usually an inherited disorder, which means it is passed on from parent to child through a specific gene. It is the most common inherited bleeding disorder. Von Willebrand disease affects about % to 1% of the U.S. population, and about three out of .   Keesler DA, Flood VH. Current issues in diagnosis and treatment of von Willebrand disease. Res Pract Thromb Haemost. Jan. 2 (1) Schneppenheim R. The pathophysiology of von Willebrand disease: therapeutic implications. Thromb Res. Suppl 1:S Grabowski EF, Curran MA, Van Cott EM.

      Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). Consequently, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis. “Von Willebrand Disease – Pipeline Insight, ” report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across Von Willebrand Disease. A detailed picture of the pipeline landscape is provided with summation of data from multiple sources with complete analysis by development stage, mechanism of.

    Von Willebrand disease and hemophilia, two conditions that are most often inherited, may also develop as a result of a medical condition. Other, rarer types of acquired bleeding disorders include deficiencies of certain factors, such as factor I, II, and V, that are named for the clotting factor causing the problem. Von Willebrand's disease is the most common inherited bleeding disorder and is generally transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding and excessive blee.


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Current Therapy of Von Willebrand"s Disease (Current Therapy of Von Willerbrand"s Disease, Vol 24, No 5) by M. M. P. Mannucci Download PDF EPUB FB2

The treatment of von Willebrand disease The treatment of hereditary VWD The objectives of therapy and specific indications in VWD bleedings The objective of the therapy in VWD deals with the correction of the abnormal platelets which are dependent on VWD and on the coagulation anomalies, by raising VWD and VIIIc F [6,24,25] plasmatic : I Buga-Corbu, C Arion.

This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis.

In addition to the current understanding of its molecular biology, this book gives particular focus to the. Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved.

This book summarizes recent research and will help to optimize the management of patients with von. Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine.

Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. Von Willebrand disease (VWD) is the most common inherited bleeding disorder with an estimated prevalence of ~1% and clinically relevant bleeding symptoms in approximatelyindividuals.

VWD is caused by a deficiency and/or defect of von Willebrand factor (VWF). Current-Therapy-Of-Von-Willebrands-Xl Adobe Acrobat Reader DCDownload Adobe Acrobat Reader DC Ebook PDF:Download free Acrobat Reader DC software the only PDF viewer that lets you read search print and interact with virtually any type of PDF file.

Von Willebrand disease (VWD) is an inherited bleeding disorder that is caused by deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and also binds and stabilizes blood clotting factor VIII (FVIII) in the circulation.

Therefore, defects in VWF can. What is von Willebrand DisEASE (VWD). Von Willebrand disease (VWD - also known as von Willebrand disorder) is an inherited bleeding disorder. People with VWD have a problem with a protein in their blood called von Willebrand factor (VWF) that helps control bleeding.

They do not have enough of the protein or it does not work the way it should. Von Willebrand disease (vWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions.

It arises from a deficiency in the quality or quantity of von Willebrand factor (vWF), a multimeric protein that is required for platelet well as humans, it is known to affect several breeds of dogs. Introduction: Von Willebrand disease (VWD) is the most common autosomally inherited bleeding disorder, characterized by a quantitative or qualitative defect of the multimeric adhesive glycoprotein von Willebrand factor (VWF).The mainstay of treatment of bleeding in VWD involves the use of desmopressin and plasma-derived factor VIII (FVIII)-VWF concentrates.

Von Willebrand disease (VWD) is a disorder that makes it hard for your blood to clot. This happens because you don’t have enough of a clotting protein called von Willebrand factor (VWF). Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition.

Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved.

This book summarizes recent research and will help to optimize the management of patients with von. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy.

Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and s: 2.

Acquired von Willebrand disease most frequently affects individuals over 40 who do not have a prior history of abnormal bleeding.

Platelet-type von Willebrand disease (PT-VWD), also known as pseudo-von Willebrand disease, is an extremely rare genetic disorder characterized by. Von Willebrand’s disease is a bleeding disorder that results from the lack of von Willebrand factor (vWF), a protein needed to help platelets clump together and seal broken blood vessels.

Affected dogs have varying amounts of vWF. Doberman Pinschers are the most common breed affected but they are mildly affected compared to Scottish terriers and Chesapeake Bay retrievers. Von Willebrand disease can have different inheritance patterns.

Most cases of type 1 and type 2 von Willebrand disease are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. Type 3, some cases of type 2, and a small number of type 1 cases of von Willebrand disease are inherited in an autosomal.

This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes.

Having von Willebrand disease (VWD) doesn’t hold Ray Pierce back. The year-old junior at Catholic University of America in Washington, DC, swims freestyle sprint and breaststroke for his college swim team. Throughout his life, he has done gymnastics, played baseball (as third baseman and outfielder), run track and played basketball, and he continues with his favorite sport, karate.

Multimeric analysis of Factor VIII/von Willebrand Factor in the diagnosis of von Willebrand's disease. IN: Clinical Laboratory Assays: New Technology and Future Directions.

Nakamura,R.M., W.R. Dito and Tucker eds. Masson Publishing USA, Inc. From the National Heart Lung and Blood Institute, National Institutes of Health. These guidelines for diagnosis and management of von Willebrand disease (VWD) were developed for practicing primary care and specialist clinicians—including family physicians, internists, obstetrician-gynecologists, pediatricians, and nurse-practitioners—as well as hematologists and laboratory medicine.

This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis.

In addition to the current understanding of its molecular biology, this book gives particular focus to the.Current hormonal and non-hormonal therapies are limited by ineffectiveness and intolerance.

Few data exist regarding von Willebrand factor (VWF), typically prescribed when other treatments fail. The lack of effective therapy for menorrhagia remains the greatest unmet healthcare need in women with VWD.The article represents a review of recent data about the therapy of von Willebrand disease in children and adolescents (hereditary as well as acquired forms of the disease).